Description: A competitive ELISA for quantitative measurement of Human Anti centriole and centrosome antibody IgG in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Description: The G9a Homogeneous Assay Kit is designed to measure the activity of G9a (also known as EHMT2 or KMT1C) for screening and profiling applications, using AlphaLISA® technology. The key to the G9a Homogeneous Assay_x000D_Kit is a highly specific antibody that recognizes methylated substrate. With this kit,_x000D_only three simple steps on a microtiter plate are required for methyltransferase_x000D_detection. First, a sample containing G9a enzyme is incubated with the biotinylated_x000D_substrate for one hour. Next, acceptor beads and primary antibody are added, then_x000D_donor beads, followed by reading the Alpha-counts.

Description: The p300 Homogeneous Assay Kit contains an AlphaLISA® assay designed for screening inhibitors of p300 in a convenient 384-well format. This efficient method requires no time-consuming washing steps. Only a few steps are needed. The assay is based on the enzymatic transfer of an acetyl group from acetyl CoA to a specific lysine residue within a biotinylated peptide substrate. After incubation with p300, the sample is incubated with a combination of an antibody that specifically binds the acetylated peptide and acceptor beads that bind the antibody. This is followed by incubation with streptavidin-labeled donor beads and reading of the Alpha-counts.

Description: The EZH2 Homogeneous Assay Kit is designed to measure activity of the EZH2 for screening and profiling applications, using AlphaLISA® technology. The key to the EZH2 Homogeneous Assay Kit is a highly specific_x000D_antibody that recognizes methylated substrate. With this kit, only three simple steps on a_x000D_microtiter plate are required for methyltransferase detection. First, a sample containing_x000D_EZH2 enzyme is incubated with the histone substrate for one hour. Next, acceptor beads_x000D_and primary antibody are added, then donor beads, followed by reading the Alpha-counts.

Description: The PD-1:PD-L1 Homogeneous Assay Kit is designed to measure the_x000D_inhibition of PD-1 binding to PD-L1. With this kit, only three simple steps on a microtiter_x000D_plate are required. First, a sample containing PD-1 and an inhibitor of choice is incubated with_x000D_the biotinylated PD-L1 for 60 minutes. Next, acceptor beads are added, then donor beads,_x000D_followed by reading the Alpha-counts.

Description: The PD-1:PD-L2 Homogeneous Assay Kit is designed to measure the_x000D_inhibition of PD-1 binding to PD-L2. With this kit, only three simple steps on a microtiter_x000D_plate are required. First, a sample containing PD-1 and an inhibitor of choice is incubated with_x000D_the biotinylated PD-L2 for 60 minutes. Next, acceptor beads are added, then donor beads,_x000D_followed by reading the Alpha-counts.

Description: The PRMT5 Homogeneous Assay Kit is designed to measure PRMT5 activity for screening and profiling applications. PRMT5 is a histone methyltransferase that exhibits methylation activity toward H4-R3. The key to the PRMT5 Homogeneous Assay Kit is a highly specific antibody that recognizes methylated substrate. With this kit, only three simple steps on a microtiter plate are required for methyltransferase detection. First, a sample containing PRMT5 enzyme is incubated with the biotinylated substrate for two hours. Next, acceptor beads and primary antibody are added, then donor beads, followed by reading the Alpha-counts.

Description: The PRMT1 Homogeneous Assay Kit is designed to measure the activity of PRMT1 for screening and profiling applications, using AlphaLISA® technology. The key to the PRMT1 Homogeneous Assay Kit is a highly specific antibody that recognizes methylated substrate. With this kit, only three simple steps on a microtiter plate are required for methyltransferase detection. First, a_x000D_sample containing PRMT1 enzyme is incubated with the biotinylated substrate for one_x000D_hour. Next, acceptor beads and primary antibody are added, then donor beads, followed by_x000D_reading the Alpha-counts.

Description: The PRMT3 Homogeneous Assay Kit is designed to measure the activity of PRMT3 for screening and profiling applications, using AlphaLISA® technology. The_x000D_key to the PRMT3 Homogeneous Assay Kit is a highly specific antibody that recognizes_x000D_methylated substrate. With this kit, only three simple steps on a microtiter plate are_x000D_required for methyltransferase detection. First, a sample containing PRMT3 enzyme is_x000D_incubated with the biotinylated substrate for one hour. Next, acceptor beads and primary_x000D_antibody are added, then donor beads, followed by reading the Alpha-counts.

Description: The PRMT8 Homogeneous Assay Kit is designed to measure the activity of PRMT8 for screening and profiling applications, using AlphaLISA® technology. The key to the PRMT8 Homogeneous Assay Kit is a highly specific antibody that recognizes methylated substrate. With this kit, only three simple steps on a microtiter plate are required for methyltransferase detection. First, a sample containing PRMT8 enzyme is incubated with the biotinylated substrate for one hour. Next, acceptor beads and primary antibody are added, then donor beads, followed by reading the Alpha-counts.

Description: The SMYD3 Homogeneous Assay Kit is designed to measure SMYD3 activity_x000D_for screening and profiling applications. SMYD3 is a histone methyltransferase that promotes diand_x000D_trimethylation of lysine4 of histone H3. It also exhibits methylation activity toward a lysine_x000D_residue of MAPK/ERK Kinase Kinase 2 (MAP3K2). The key to_x000D_the SMYD3 Homogeneous Assay Kit is a highly specific antibody that recognizes methylated_x000D_substrate. With this kit, only three simple steps on a microtiter plate are required for_x000D_methyltransferase detection. First, a sample containing SMYD3 enzyme is incubated with the_x000D_substrate for three hours. Next, acceptor beads and primary antibody are added, then donor_x000D_beads, followed by reading the Alpha-counts.

Description: The PRMT4 Homogeneous Assay Kit is designed to measure PRMT4 activity for screening and profiling applications. PRMT4 (CARM1) is an arginine methyltransferase and dual functional coregulator that facilitates transcription initiation by methylation of Arg17 and Arg26 of histone H3. The PRMT4 Homogeneous Assay Kit comes in a convenient AlphaLISA® format, with His-tagged PRMT4 substrate, primary antibody, methylation assay buffer, and purified PRMT4 for 384 enzyme reactions. The key to the PRMT4 Homogeneous Assay Kit is a highly specific antibody that recognizes methylated substrate. With this kit, only three simple steps on a microtiter plate are required for methyltransferase detection. First, a sample containing PRMT4 enzyme is incubated with the substrate. Next, acceptor beads and primary antibody are added, then donor beads, followed by reading the Alpha-counts.

Description: The PRMT9 Homogeneous Assay Kit is designed to measure PRMT9 activity for screening and profiling applications. PRMT9 is a histone methyltransferase that exhibits methylation activity toward an arginine residue of SAP145. The PRMT9 Homogeneous Assay Kit comes in a convenient AlphaLISA® format, with GST-tagged PRMT9 substrate, primary antibody, methylation assay buffer, and purified PRMT9 for 384 enzyme reactions. _x000D_ The key to the PRMT9 Homogeneous Assay Kit is a highly specific antibody that recognizes methylated substrate. With this kit, only three simple steps on a microtiter plate are required for methyltransferase detection. First, a sample containing PRMT9 enzyme is incubated with the substrate. Next, acceptor beads and primary antibody are added, then donor beads, followed by reading the Alpha-counts.

Description: The JMJD2D Homogeneous Assay Kit is designed to measure JMJD2D activity for screening and profiling applications. JMJD2D, also known as KDM4D, is a JumonjiC (JmjC) domain containing histone lysine demethylase that exhibits demethylation activity toward H3-K₉Me³ and H3-K₃₆Me³. The key to the JMJD2D Homogeneous Assay Kit is a highly specific antibody that recognizes demethylated substrate. With this kit, only three simple steps on a microtiter plate are required for methyltransferase detection. First, a sample containing JMJD2D enzyme is incubated with the biotinylated substrate. Next, acceptor beads and primary antibody are added, then donor beads, followed by reading the Alpha-counts._x000D_ Our histone demethylase assays utilize highly specific antibodies that recognize demethylated products. First, a sample containing the enzyme is incubated with a biotinylated substrate. Next, acceptor beads and primary antibody are added, then donor beads, followed by reading the Alpha-counts, as shown above.

Description: The JMJD1B Homogeneous Assay Kit is designed to measure JMJD1B activity for screening and profiling applications. JMJD1B, also known as JHDM2B and KDM3B, is a JumonjiC (JmjC) domain containing histone lysine demethylase that exhibits demethylation activity toward H3-K₉Me³ and H3-K₃₆Me³. TThe key to the JMJD1B Homogeneous Assay Kit is a highly specific antibody that recognizes demethylated substrate. With this kit, only three simple steps on a microtiter plate are required for methyltransferase detection. First, a sample containing JMJD1B enzyme is incubated with the biotinylated substrate. Next, acceptor beads and primary antibody are added, then donor beads, followed by reading the Alpha-counts._x000D_Our histone demethylase assays utilize highly specific antibodies that recognize demethylated products. First, a sample containing the enzyme is incubated with a biotinylated substrate. Next, acceptor beads and primary antibody are added, then donor beads, followed by reading the Alpha-counts, as shown above.